中国修复重建外科杂志

中国修复重建外科杂志

经皮氧分压在瘢痕评估中的应用

查看全文

目的 总结经皮氧分压(transcutaneous oxygen pressure,TcPO2)测量在瘢痕评估中的应用以及研究进展。 方法 查阅国内外与瘢痕以及 TcPO2 相关的文献,并进行总结分析。 结果 组织中缺氧环境在瘢痕发生发展过程起重要作用,TcPO2 能准确反映瘢痕组织内的氧分压情况,已用于瘢痕成熟度评估、指导瘢痕治疗以及研究缺氧对瘢痕发生发展的影响方面。 结论 TcPO2 测量在瘢痕评估、治疗以及缺氧与瘢痕发生机制研究中有重要意义。

Objective To review the application and research progress of transcutaneous oxygen pressure (TcPO2) in scar assessment. Methods The original articles about scar and TcPO2 were reviewed and analyzed. Results Hypoxia environment plays an important role in the progression of scar tissue. TcPO2 can accurately reflect the oxygen tension of scar tissue, which is of great significance in the assessment of scar maturity, the guidance of scar treatment, and the study of correlations between hypoxia and the progression of scar. Conclusion TcPO2 measurement is important in the study of scar evaluation, treatment, and correlation between hypoxia and scar formation.

关键词: 瘢痕; 经皮氧分压; 微血管; 瘢痕评估

Key words: Scar; transcutaneous oxygen pressure; microvessel; scar assessment

引用本文: 周易, 汤宋佳, 曹谊林, 张菊芳. 经皮氧分压在瘢痕评估中的应用. 中国修复重建外科杂志, 2018, 32(12): 1615-1618. doi: 10.7507/1002-1892.201810098 复制

登录后 ,请手动点击刷新查看全文内容。 没有账号,
1. Brown BC, McKenna SP, Siddhi K, et al. The hidden cost of skin scars: quality of life after skin scarring. J Plast Reconstr Aesthet Surg, 2008, 61(9): 1049-1058.
2. Sheridan RL, Hinson MI, Liang MH, et al. Long-term outcome of children surviving massive burns. JAMA, 2000, 283(1): 69-73.
3. Rooth G. Transcutaneous oxygen tension measurements in newborn infants. Pediatrics, 1975, 55(2): 232-235.
4. Yip WL. Evaluation of the clinimetrics of transcutaneous oxygen measurement and its application in wound care. Int Wound J, 2015, 12(6): 625-629.
5. Dowd GS, Linge K, Bentley G. Measurement of transcutaneous oxygen pressure in normal and ischaemic skin. J Bone Joint Surg (Br), 1983, 65(1): 79-83.
6. Goldman RJ, Salcido R. More than one way to measure a wound: an overview of tools and techniques. Adv Skin Wound Care, 2002, 15(5): 236-243.
7. Pecoraro RE, Ahroni JH, Boyko EJ, et al. Chronology and determinants of tissue repair in diabetic lower-extremity ulcers. Diabetes, 1991, 40(10): 1305-1313.
8. Fagher K, Katzman P, Löndahl M. Transcutaneous oxygen pressure as a predictor for short-term survival in patients with type 2 diabetes and foot ulcers: a comparison with ankle-brachial index and toe blood pressure. Acta Diabetol, 2018, 55(8): 781-788.
9. Carter SA, Tate RB. The relationship of the transcutaneous oxygen tension, pulse waves and systolic pressures to the risk for limb amputation in patients with peripheral arterial disease and skin ulcers or gangrene. Int Angiol, 2006, 25(1): 67-72.
10. Andrews KL, Dib MY, Shives TC, et al. Noninvasive arterial studies including transcutaneous oxygen pressure measurements with the limbs elevated or dependent to predict healing after partial foot amputation. Am J Phys Med Rehabil, 2013, 92(5): 385-392.
11. Alster TS, Lewis AB, Rosenbach A. Laser scar revision: comparison of CO2 laser vaporization with and without simultaneous pulsed dye laser treatment. Dermatol Surg, 1998, 24(12): 1299-1302.
12. Oliveira GV, Chinkes D, Mitchell C, et al. Objective assessment of burn scar vascularity, erythema, pliability, thickness, and planimetry. Dermatol Surg, 2005, 31(1): 48-58.
13. Taylor B, McGrouther DA, Bayat A. Use of a non-contact 3D digitiser to measure the volume of keloid scars: a useful tool for scar assessment. J Plast Reconstr Aesthet Surg, 2007, 60(1): 87-94.
14. Fong SS, Hung LK, Cheng JC. The cutometer and ultrasonography in the assessment of postburn hypertrophic scar—a preliminary study. Burns, 1997, 23: S12-S18.
15. Kim YJ, Kim MY, Lee PK, et al. Evaluation of natural change of skin function in split-thickness skin grafts by noninvasive bioengineering methods. Dermatol Surg, 2006, 32(11): 1358-1363.
16. Nguyen DQ, Potokar T, Price P. A review of current objective and subjective scar assessment tools. J Wound Care, 2008, 17(3): 101-102.
17. Sloan DF, Brown RD, Wells CH, et al. Tissue gases in human hypertrophic burn scars. Plast Reconstr Surg, 1978, 61(3): 431-436.
18. Berry RB, Tan OT, Cooke ED, et al. Transcutaneous oxygen tension as an index of maturity in hypertrophic scars treated by compression. Br J Plast Surg, 1985, 38(2): 163-173.
19. Zheng J, Song F, Lu SL, et al. Dynamic hypoxia in scar tissue during human hypertrophic scar progression. Dermatol Surg, 2014, 40(5): 511-518.
20. Phillips TJ, Gerstein AD, Lordan V. A randomized controlled trial of hydrocolloid dressing in the treatment of hypertrophic scars and keloids. Dermatol Surg, 1996, 22(9): 775-778.
21. Farjo B, Farjo N, Williams G. Hair transplantation in burn scar alopecia. Scars Burn Heal, 2015, 1: 2059513115607764.
22. Jung S, Oh SJ, Hoon Koh S. Hair follicle transplantation on scar tissue. J Craniofac Surg, 2013, 24(4): 1239-1241.
23. Unger W, Unger R, Wesley C. The surgical treatment of cicatricial alopecia. Dermatol Ther, 2008, 21(4): 295-311.
24. Gordillo GM, Sen CK. Revisiting the essential role of oxygen in wound healing. Am J Surg, 2003, 186(3): 259-263.
25. Ueda K, Yasuda Y, Furuya E, et al. Inadequate blood supply persists in keloids. Scand J Plast Reconstr Surg Hand Surg, 2004, 38(5): 267-271.
26. Kischer CW, Brody GS. Structure of the collagen nodule from hypertrophic scars and keloids. Scan Electron Microsc, 1981, (Pt 3): 371-376.
27. 宋菲, 刘英开, 王西樵. 增生性瘢痕发生和演变过程中微血管和氧分压动态变化的研究. 上海交通大学学报 (医学版), 2016, 36(11): 1553-1557.
28. Song KX, Liu S, Zhang MZ, et al. Hyperbaric oxygen therapy improves the effect of keloid surgery and radiotherapy by reducing the recurrence rate. J Zhejiang Univ Sci B, 2018, 19(11): 853-862.