中国修复重建外科杂志

中国修复重建外科杂志

聚氨酯弹性体和 Medpor 作为人工耳支架材料的力学研究

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目的对人耳廓软骨与聚氨酯弹性体材料、高密度聚乙烯材料(Medpor)进行力学性能比较,为选择合适的人工耳支架材料提供理论依据。方法将实验材料分为 3 组,分别是人耳廓软骨组(A 组)、聚氨酯弹性体组(B 组)和 Medpor 组(C 组),每组 6 个样本。利用 Instron5967 力学试验机进行压缩、拉伸试验,分别测量压缩参数值(包括屈服应力、屈服载荷、弹性模量、屈服压缩率、2 MPa 压缩率和 10% 应变压缩应力),拉伸参数值(包括屈服应力、屈服载荷、弹性模量、屈服伸长率、2 MPa 伸长率和 1% 应变拉伸应力),并进行比较。结果压缩试验:B 组样本全程未见明显屈服点,A、C 组样本可见明显屈服点。A、C 组屈服应力、屈服载荷差异无统计学意义(P>0.05);但 C 组屈服压缩率显著低于 A 组(P<0.05),弹性模量显著高于 A 组(P<0.05)。3 组材料 2 MPa 压缩率组间比较差异均有统计学意义(P<0.05),从大到小依次为 B、A、C 组;C 组 10% 应变压缩应力显著高于 A、B 组(P<0.05),A、B 组间差异无统计学意义(P>0.05)。拉伸试验:B 组材料具有极强的伸长性能。A、B 组屈服应力显著高于 C 组,弹性模量和 1% 应变拉伸应力显著低于 C 组(P<0.05);A、B 组间差异无统计学意义(P>0.05)。3 组间屈服载荷比较差异无统计学意义(P>0.05);屈服伸长率 3 组间比较差异均有统计学意义(P<0.05),从大到小依次为 B、A、C 组。2 MPa 伸长率 B 组显著高于 A、C 组(P<0.05),A、C 组间差异无统计学意义(P>0.05)。结论与 Medpor 材料相比,聚氨酯弹性体是更理想的人工耳支架材料。

ObjectiveBy comparing the mechanics of human auricular cartilage, polyurethane elastic material, and high density polyethylene material (Medpor), to produce theoretical proof on choosing optimal artificial auricular scaffold materials.MethodsThe experimental materials were divided into 3 groups with 6 samples in each: the auricular cartilage group (group A), the polyurethane elastic material group (group B), and the Medpor group (group C). With an Instron5967 mechanical testing machine, compression and tensile testing were performed to respectively measure values of compression parameters (including yield stress, yield load, elastic modulus, yield compressibility, compressibility within 2 MPa, and compression stress within 10% strain) and values of tensile parameters (including yield stress, yield load, elastic modulus, yield elongation, elongation within 2 MPa, tensile stress within 1% strain) for comparison.ResultsCompression testing: no obvious yield points were observed in the whole process in samples of group B, while obvious yield points were observed in samples of groups A and C. There was no significant difference between groups A and C with respect to yield stress and yield load (P>0.05); while the yield compressibility in group C was significantly lower than that in group A (P<0.05) and the elastic modulus in group C was significantly higher than that in group A (P<0.05). There was a significant difference with respect to compressibility within 2 MPa of materials among the 3 groups (P<0.05), the high, medium, and low values go to groups B, A, and C respectively. The compression stress within 10% strain in group C was significantly higher than that in groups A and B (P<0.05), and there was no significant difference between that in groups A and B (P>0.05). Tensile testing: the materials in group B had extremely high tensile strength. The yield stress in groups A and B was significantly higher than that in group C (P<0.05), and the elastic modulus and tensile stress within 1% strain were significantly lower than those in group C (P<0.05); but no significant difference was found between those in groups A and B (P>0.05). There was no significant difference with respect to yield load among the 3 groups (P>0.05); but there was significant difference with respect to yield elongation among the 3 groups (P<0.05), and the high, medium, and low values go to groups B, A, and C respectively. The elongation within 2 MPa in group B was significantly higher than that in groups A and C (P<0.05), and there was no significant difference between that in groups A and C (P>0.05).ConclusionCompared with the Medpor, the polyurethane elastic material is a more ideal artificial auricular scaffold material.

关键词: 聚氨酯; Medpor; 人工耳支架; 生物力学

Key words: Polyurethane; Medpor; artificial auricular scaffold; biomechanics

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